NIH logo                              

Reproducibility of Data Collection and Analysis

Modern Technologies in Genome Technology: Potentials and Pitfalls

Thursday, June 4, 2015
Natcher Conference Center, Building 45, Room E1/E2
Bethesda, Maryland

                              IRP logo

This is the third of three planned workshops sponsored by the NIH Office of the Director on the important topic of reproducibility, the subject of recent editorials in leading scientific journals. (The first is on cell biology; the second is on structural biology.)

The purpose of these workshops is to educate the NIH intramural research community about what advanced technologies can accomplish and the kinds of reproducibility problems that can arise; provide a cautionary note to scientists who hope to use but are inexperienced with various new modeling techniques; and educate others who are attempting to interpret results in the literature.

The meeting agenda is below.

We have invited several world-class scientists who will speak about important technologies in genomic research. In addition, we have invited editors from scientific journals covering genomic research to moderate sessions and discuss issues with data reproducibility in the scientific literature. We encourage you to mark this event on your calendar, and we hope you will be able to attend, either in person or through the videocast at (available the day of the event).

We welcome our colleagues beyond the NIH to watch the videocast, too, which also will be archived. If you have any questions, please e-mail Dr. Paul Liu.

To help us gauge attendance, please register online in advance of the meeting at

Nature article
Nature commentary (Collins & Tabak)


Thursday, June 4, 2015

Natcher Conference Center, Building 45, Room E1/E2

12:30 p.m.
Opening remarks
Eric Green, NHGRI Director

12:40 p.m.
Session 1: Genomics in clinical research
Moderator: David Nelson (American Journal of Human Genetics)
Speaker #1: Stephen Chanock (NCI-DCEG)
Speaker #2: Les Biesecker (NHGRI)

1:40 p.m.
Session 2: Whole genome and exome sequencing
Moderator: Hillary Sussman (Genome Research)
Speaker #1: Jim Mullikin (NHGRI)
Speaker #2: James Taylor (Hopkins)

2:40 p.m.

3:00 p.m.
Session 3: ChIP-Seq and other epigenomic tools
Moderator: Kyle Vogan (Nature Genetics)
Speaker #1: Keji Zhao (NHLBI)
Speaker #2: Shirley Liu (Harvard)

4:00 p.m.
Session 4: RNA-Seq
Moderator: Natalie de Souza (Nature Methods)
Speaker #1: Paul Meltzer (NCI)
Speaker #2: Chris Mason (Cornell)

5:00 p.m.
Closing remarks
Stephen Chanock (NCI-DCEG)

DHHS logo