Astute Clinician Lectures The Gordon Lectures The G. Burroughs Mider Lectures
Cultural Lectures The Marjory Guthrie Lectures The NIH Director's Lectures
Dyer Lectures The Marc Keller Lectures The NIH Director's Seminar Series
Ehrlich Lectures The George Khoury Lectures The Percy Julian Centennial Lecture
Fogarty International Lectures The Kinyoun Lectures The Margaret Pittman Lecture
The Jules Freund Lectures The Seymour J. Kreshover Lectures NIH Alumni Assn. Shannon Lecture
The GM Laureates Lectures The Florence Mahoney Lectures The DeWitt Stetten, Jr. Lecture
  The Wednesday Afternoon Lectures (WALS)

 

 

 

Speaker Date Institution Title
The NIH Director's Astute Clinician Lecture
Beckwith, J. Bruce 10/15/1998 Loma Linda Univ. The Link Between Teratogenesis and Carcinogensis: Lessons from the Wilms Tumor Study
Steere, Allen C. Jr. 11/3/1999 Tufts The Elucidation of Lyme Arthritis
New, Maria I. 12/13/2000 Cornell The patients who taught me and led to my discoveries in congenital adrenal hyperplasia
Druker, Brian 11/7/2001 Oregon Health Sci. Univ. STI571: A Tyrosine Kinase Inhibitor for the Treatment of Chronic Myelogenous Leukemia (CML) Validating the Promise of Molecularly Targeted Therapy
       
       
The NIH Director's Cultural Lecture
Seaborg, Glenn T. 11/17/1962
Status of Transuranium Elements
Merton, Robert E. 2/5/1964
Studies in the Sociology of Science
Wiesner, Jerome B. 12/15/1964
Research in Education
Price, Derek deSolla 2/9/1966
Quantitative Measures of Size and Significance and Relatedness of Scientific Literature
Wienberg, Alvin M. 3/15/1972
Science and Trans-Science
Mead, Margaret 10/17/1973
The Changing Significance of Territoriality in Human Societies
Leakey, Mary 3/2/1977
Early Man
Elsen, Albert 5/13/1979
In Rodin’s Studio
Rivlin, Alice 12/5/1984
Managing the Deficit
Ripley, S. Dillon 12/12/1984
Twenty Years a’Growing
Bromley, D. Allan 1/7/1993 Off.Sci&Tech.Pol. Federal Science and Technology Policy
Alexander, Jane 5/8/1994 Nat.Endow.forTheArts The Health of the Spirit
Nuland, Sherwin B. 4/25/1995 Yale To See Ourselves as Others See Us: The Artist Looks at the Doctor
Gell-Mann, Murray 5/6/1996 Santa Fe Inst. From Simplicity to Complexity
Tannen, Deborah 10/28/1996 Georgetown Women and Men in Conversation: A Linguistic Approach
Pinsky, Robert 5/25/1998 Boston Univ. Poetry Reading with Commentary
Pinker, Steven 11/4/1998 MIT Words and Rules: The Ingredients of Language
Sen, Amartya K. 5/26/1999 Cambridge Conflicting Principles of Health Evaluation
Diamond, Jared 9/18/2000 UCLA Why did human history unfold differently on different continents for the last 13,000 years?
The Dyer Lecture
Beadle, George W. 6/21/1951
Genetic Control of Metabolism
Burnet, Sir F. MacFarlane 10/29/1952
The Virus and the Cell
Dubos, Rene Jules 11/22/1953
The Gold-Headed Cane in the Laboratory
Enders, John Franklin 11/17/1954
Recent Observations on the Behavior of Tissue Culture of Certain Viruses Pathogenic to Man
Pillemer, Louis 1/31/1956
The Properdin System
Meyer, Karl F. 2/19/1957
The Natural History of Plague and Psittacosis
Shope, Richard E. 11/5/1957
Influenza: History, Epidemiology and Speculation
McDermott, Walsh 12/16/1958
Microbial Persistence and Latency
Coons, Albert H. 12/1/1959
Immunofluorescence
Macdonald, George 11/15/1960
Epidemiologic Models in Vector-Borne Disease Studies
Hotchkiss, Rolliln D. 1/10/1962
Messages in Macromolecules
Luria, Salvador E. 4/24/1963
How Does a Virus Work?
Rubin, Harry 4/29/1964
the Malignant Transformatin of Cells by Viruses
Langmuir, Alexander D. 4/7/1965
The Territory of Epidemiology
Habel, Karl 4/27/1966
Viral Oncogenesis or Subversion at the Cellular Level
Good, Robert Alan 4/26/1967
Development and Involution of Lymphoid Tissue and Immunologic Capacities
Spiegelman, Sol 4/24/1968
Test-Tube Studies of a Self-Duplicating RNA Molecule
Lwoff, André 4/9/1969
Viral and Cellular Interactions: The Mechanisms of Actions of Supraoptimal Temperature on the Development of Poliovirus
Benacerraf, Baruj 12/17/1969
Cell Selection and Cooperation in the Immune Response
Green, Maurice 5/12/1971
Mechanism of Cell Transformation by DNA and RNA Tumor Viruses
Austen, K. Frank 4/19/1972
The Inflammatory Response: Appreciation of Amplification and Control Mechanisms
Kilbourne, Edwin D. 1/24/1973
Influenza: The Last of the Great Plagues-Genetic Approaches to the Understanding and Control of an Infectious Disease
Temin, Howard M. 2/6/1974
The Replication and Possible Origin of RNA Viruses with a DNA Polymerase
Gajdusek, D. Carleton 11/6/1974 NIH Kuru
McDevitt, Hugh D. 9/29/1976
Selective Expression of I Region Genes in Lymphocyte Subpopulations
Kabat, Elvin A. 3/14/1978
Structural and Genetic Approaches to the Study of Antibody Complementarity
Chanock, Robert M. 5/31/1978 NIH Influenza Virus: Recent Insights and Prospects for Effective Control
Ruddle, Frank H. 10/18/1978
Gene Transfer in Mammalian Cells
Scharff, Matthew D. 2/25/1981
Somatic Variation in Immunoglobulin Production by Mouse Myeloma Cells
Davies, David 5/12/1982
The 3-Dimensional Structure of the Antibody Molecule:Specificity and Diversity
Potter, Michael 5/12/1982
The 3-Dimensional Structure of the Antibody Molecule:Specificity and Diversity
Gallo, Robert C 12/14/1982 NIH Human Tumor Viruses: The Search for Some is Over
Miller, Louis H. 5/1/1985 NIH Malaria: Cell Surface Proteins as REceptors and Immunogens
Hood, Leroy E. 4/23/1986
The Immunoglobin Gene Superfamily and Biological Instrumentation
Fields, Bernard N. 3/11/1987
Molecular Basis of Viral Virulence
Martin, Malcolm A. 2/14/1990 NIH Retroviruses: Where did they come from and Where are they Going?
Koshland, Marian E. 5/18/1990 Berkeley Mechanism of Peptide Hormone Signalling:An Immunological Gene Model
Cooper, Max D. 5/7/1991 Univ. of Alabama A Comparative Analysis of T Cell Development
Marrack, Philippa C. 4/14/1992 Univ. Colorado The Alpha Beta T Cell Repertoire in Health and Disease
Metzger, Henry 1/4/1995 NIH Macromolecular Associations and Signal Transduction
Robbins, John B. 4/23/1996 NIH Something Old and Something New; Something Borrowed and Some Things Yet to Do
von Boehmer, Harald 4/10/1997 INSERM Lymphocyte Survival
Korsmeyer, Stanley J. 9/10/1997 Washington Univ. Cell death and the regulation of homeostasis
Dinarello, Charles A. 4/28/1999 Univ. Colorado Anti-Cytokine Therapies for Inflammatory Diseases
Bloom, Barry R. 5/3/2000 Harvard A View of Public Health and Biomedical Research
Oldstone, Michael B.A. 9/13/2000 Scripps How viruses suppress the immune system: Molecular and cellular mechanisms and consequences
Ahmed, Rafi 12/19/2001 Emory Immunological Memory: Lessons for Vaccine Development
       
       
The Paul Ehrlich Lectures
Prusiner, Stanley B. 4/26/1995 UCSF Present State of Prions
Marshall, Barry J. 4/17/1996 Univ. of Virginia New Magic Bullets in the Fight Against Gastritis
Hayaishi, Osamu 4/2/1997 OsakaBiosciInst Secrets of Sleep: Molecular Mechanisms of Sleep-Wake Regulation
Zasloff, Michael 5/7/1998 Magainin Pharm.Inc Discovery of Antibiotic Systems in Animals
Fogarty International Lectures
Eigen, Manfred 5/31/1995 Max Planck Sorting Single Molecules in Evolutionary Research
Kafatos, Fotis C. 5/28/1997 EuroMolecBiol.Lab The New Genetics in the Study of Organisms Important to Humans: A Case Study of Mosquito-Malaria-Human Interactions
The Jules Freund Lectures
Chase, Merrill W. 11/15/1961
Studies of Hypersensitivity to Simple Chemical Allergens
Heidelberger, Michael 10/17/1962
Chemical Constitution and Immunological Specificity of Polysaccharides
Witebsky, Ernest 10/7/1963
Autosensitization in Animals and Man
Dienes, Louis L. 10/7/1964
Pleuropneumonia-like Organisms and L-forms of Bacteria
Dubos, Rene Jules 9/29/1965
Mechanisms of Intracellular Infection
Haurowitz, Felix 10/13/1966
Problems of Antibody Biosynthesis
Grabar, Pierre 10/20/1967
Immunochemical Analysis of Tissue Constituents
Sabin, Albert B. 11/6/1968
Whither the Search fo Viral Etiology of Human Cancer?
Kabat, Elvin A. 11/3/1969
Blood Group A.B.H. and Le Substances--Their Chemistry and the Nature of their Reaction with Antibodies and other Specific Hemagglutinins
Eagle, Harry 10/19/1970
Serum, pH, and the Contact Inhibition of Normal Human Cells
Eisen, Herman N. 11/18/1971
Myeloma Proteins as Antibodies and Tumor-Specific Antigens
Thomas, Lewis 11/17/1972
Mycoplasmas as Candidates for Vascular Pathogenicity
Koprowski, Hilary 11/26/1974
The Task of Seeing the Virus and Host as Non-Separate Realities
The GM Cancer Research Foundation Laureates Lectures
Bagshaw, Malcolm 6/20/1996 Stanford
Davis, Mark M. 6/20/1996

Kolodner, Richard D. 6/20/1996 UCSD
Mak, Tak-Wah 6/20/1996 Univ. of Toronto
Modrich, Paul L. 6/20/1996 Duke
Walsh, Patrick 6/20/1996 Johns Hopkins
Folkman, M. Judah 5/11/1997 Harvard
Nurse, Paul 5/11/1997 Imp.CancerRes.Fund
Suit, Herman D. 5/11/1997 Harvard
Hershko, Avram 6/7/2000 TechnionIsrael Inst of Tech
Varshavsky, Alexander 6/7/2000 CalTech
Vogelstein, Bert 6/7/2000 Johns Hopkins
Wall, Monroe E. 6/7/2000 Res. Triangle Inst
Wani, Mansukh C. 6/7/2000 Res. Triangle Inst
The Gordon Lectures
Hennekens, Charles H. 9/13/1995 Harvard Aspirin in the secondary and primary prevention of cardiovascular disease
Fraumeni, Joseph F. 11/13/1996 NIH Epidemiology of Cancer: An Interdisciplinary Approach
MacCluer, Jean W. 9/24/1997 UTexas From Epidemiology to Gene Discovery: Finding Genes for Complex Diseases
Sommer, Alfred 1/27/1999 Johns Hopkins Epidemiology in the Cause of Vitamin A: Science to Practice
Willett, Walter 5/5/1999 Harvard Diet and Heart Disease: Have We Misled the Nation?
Cummings, Steven 4/12/2000 UCSF New Technology and a Two-Edged Sword: How Bone Densitometry has Revolutionized and Impeded Understanding and Prevention of Osteoporotic Fractures
DeMets, David L. 4/18/2001 Univ. of Wisconsin
Peto, Richard 6/26/2002 Oxford Halving Premature Death
       
The Majorie Guthrie Lecture in Genetics
Baltimore, David 5/11/1983
Illumination of Disease Processes Through Molecular Genetics
Bloom, Floyd E. 4/19/1984 Scripps Molecular Approaches to the Characterization of Neuronal Function
Martin, Joesph B. 4/2/1985
Recent Studies in Huntington’s Disease
Benzer, Seymour 4/10/1986
Genes, Neurons, and Behavior in Drosophila
Kandel, Eric R. 6/10/1987
The Long and Short of Long-Term Memory
Lieber, Charles S. 11/1/1996
Hepatic and Other Medical Disorders of Alcoholism: From Pathogenesis to Treatment
Schuckit, Marc A. 11/13/1997
A Prospective Study of Genetic and Environmental Influences in Alcoholism: Working Towards Prevention
Li, Ting-Kai 11/19/1998 Indiana Univ. Pharmacogenetics of Responses to Alcohol and Genes That Influence Alcohol Drinking
The George Khoury Lectures
Sharp, Phillip A. 11/20/1995 MIT RNA Splicing and Biology
Vogelstein, Bert 12/11/1996 Johns Hopkins Molecular Aspects of Colon Cancer
Baltimore, David 12/10/1997 MIT Cell Life and Cell Death
Howley, Peter 12/16/1998 Harvard Papillomaviruses, Cancer and Ubiquitination
Tjian, Robert 9/29/1999 Berkeley The Biochemistry of Eukaryotic Transcription: More Surprises and Complexities
Weinberg, Robert A. 12/6/2000 MIT Creation of human cancer cells
Livingston, David M 11/28/2001 Harvard Molecular and Biological Analyses of BRCA1 Function
       
       
The Kinyoun Lectures
Eberhard, Hans J. Muller 4/24/1979
The Role of Complement in Natural Resistance to Infections
Zinkernagel, Rolf M. 5/8/1979
Cell-Mediated Immunity to Intracellular Parasites and Polymorphic Major Transplantation Antigens
Billingham, Rupert E. 11/27/1979
Transplantation Experiments in Nature and Their Biological Significance
Horstman, Dorothy 3/5/1980
Fatal Infectious Mononucleosis and Polyclonal B Cell Lymphoma
Falkow, Stanley 5/5/1980
The Molecular Cloning of E.Coli Enterotoxin Genes
Hood, Leroy E. 12/19/1980
Antibody Genes and Strategies for their Expression
Dixon, Frank J. 4/3/1981
Murine SLE: A Model for Autoimmunity
Cohen, Stanley N. 12/3/1981 Stanford Gene Expression in Heterospecific Hosts: Strategies and Surprises
Nathenson, Stanley G. 5/14/1984
Murine Major Histocompatibility Complex:Polymorphism, Diversity, Complexity
McDevitt, Hugh D. 4/10/1987
Regulation of Immunity by Class II MHC Antigens
Bloom, Barry R. 11/20/1990
Immunology of a Third-World Disease
Cohen, Zanvil A 11/21/1991
Cell-Mediated Immunity: From Bench to Bedside
Cooper, Max D. 9/1/1993 Univ. of Alabama Lymphocyte Differentiation Pathways: Changing Paradigms
Vitetta, Ellen S. 10/20/1994
Antibodies as Carriers of Toxins and as Agaonists in Cancer Therapy
Alt, Frederick W. 11/3/1995 Harvard Mutational Analysis of Lymphocyte Differentiation and VDJ Recombination
Glimcher, Laurie 10/6/2000 Harvard T Helper Cells: Genes and Development
The Seymour J. Kreshover Lecture
Fell, Dame Honor B. 9/22/1983
The Promotion and Inhibition of Collagen Breakdown in Synovial Tissue
Curtiss, Roy III 9/17/1984
Genetic Analysis of the Virulence of Streptococcus Mutans: Prospects for an Anticaries Vaccine
Genco, Robert J. 9/10/1985

Mandel, Irwin 9/24/1986
The Role of Saliva in Maintaining Oral Homeostasis
Slavkin, Harold C. 9/22/1987
Gene Regulation in the Development of Oral Tissues
Gibbons, Ronald J. 9/26/1988
Bacterial Adhesion to Oral Tissues: A Model for Infectious Diseases
Greenspan, Deborah 5/13/1989
Pathogens, Probes, and Perceptions: The Story of Multidisiplinary AIDS Research
Greenspan, John 5/13/1989
Pathogens, Probes, and Perceptions: The Story of Multidisiplinary AIDS Research
Bartoshuk, Linda 5/30/1990
The Sense of Taste: New Directions for Dentistry
Melzack, Ronald 5/4/1991
Memory Mechanisms and Pain
Williamson, Robert 5/4/1991
Molecular Genetics and Craniofacial Development
Mestecky, Jiri 5/16/1992 Univ. of Alabama Mucosal Immunology: Expectations for the 90’s
Lumsden, Andrew 1/22/1996
The Life and Death of the Cranial Neural Crest
Baron, Roland 5/11/1997
Molecular Mechanisms of Bone Resorption
The Florence Mahoney Lectures
Thomas, Lewis 1/1/1987

Their, Samuel 1/1/1988

Wilson, Edward Osborne 1/1/1989

Sabin, Albert 1/1/1990

Singer, Maxine 1/1/1991

Rowe, John 1/1/1992

Ames, Bruce 1/1/1993

Pereira-Smith, Olivia 1/1/1994

Johnson, Eugene 1/1/1995

Barrett-Connor, Elizabeth L 9/25/1996 UCSD The Gender Gap: Why do Women Have Less Heart Disease than Men?
Schlessinger, David 1/1/1997

Prusiner, Stanley B. 10/14/1998 UCSF Prion Biology and Diseases: A Saga of Skeptical Scientists, Mad Cows, and Laughing Cannibals
Hsiao, Karen 1/1/1999

Hutton, Mike 1/1/1999

Snowdon, David 1/1/1999

Tanzi, Rudy 1/1/1999

Kenyon, Cynthia 9/25/2000 UCSF Genes from the fountain of youth
Gage, Fred H. 3/7/2001 Salk Institute Neurogenesis and regeneration in the adult nervous system

Kandel, Eric

Greengard, Paul

6/12/2002

Columbia University

Rockefeller University

Molecular Biology of Memory and Its Disorders: Some Societal Implications

The Neurobiology of Slow Synaptic Transmission

       
The G. Burroughs Mider Lectures
Tomkins, Gordon M. 12/11/1968 NIH Control of Gene Activity in Higher Organisms
Law, Lloyd W. 3/11/1970 NIH Tumor Antigens: Their Origins, Characteristics and Significance
Brady, Roscoe O. 12/16/1970 NIH Genetic Mismanagement of Complex Lipids
MacLean, Paul D. 2/9/1972 NIH Survival Mechanisms of the Triune Brain: Some Hopeful Aspects
Rowe, Wallace P. 3/14/1973 NIH Genetic Factors in the Transmission and Expression of Murine Leukemia Virus
Pastan, Ira H. 11/7/1973 NIH Cyclic AMP and the Transformation of Cells
Neufeld, Elizabeth 10/9/1974 NIH Inherited Lysosomal Disorders Studied in Cell Culture
Piez, Karl A. 9/10/1975 NIH Collagen: Its Chemistry, Structure and Function
Singer, Maxine F. 5/18/1977 NIH Monkey Business: Sequences in the Monkey Genome and their Interaction with Simian Virus 40 DNA
Leder, Philip 11/2/1977 NIH A Close and Surprising Look at the Mammalian Genome
Roth, Jesse 9/13/1978 NIH Receptor Disorders in Man
Vaughan, Martha 11/17/1979 NIH Regulation of Cyclic Nucleotide Metabolism
Waldmann, Thomas 2/27/1980 NIH The Control of the Immune Response:Regulatory Cellular Interactions and the Control of Lymphocyte Differentiation
Sokoloff, Louis 12/10/1980 NIH Metabolic Mapping of Local Functional Activity in the Central Nervous System
Paul, William E. 9/15/1982 NIH Living with Lymphocytes, or B Lymphocytes and How They Grow
Evarts, Edward V. 4/18/1984 NIH Movement, Mood, and Memory:Linked Functions in the Mammalian Brain
Khoury, George 9/12/1984 NIH Enhancers: Regulatory Elements in Eukaryotic Gene Expression
Korn, Edward D. 12/4/1985 NIH Biochemical Regulation of Actinomycin-Dependent Cell Motility
Gellert, Martin 3/5/1986 NIH Why is DNA Supercoiled?
Dawid, Igor B. 2/11/1987 NIH Molecular Embryology: New Approaches to Old Questions
Martin, George R. 6/22/1988 NIH Basement Membranes: Key Determinants of Differentiation and Their Role in Cancer Metastasis
Felsenfeld, Gary 11/15/1989 NIH Switching Globin Genes On and Off:Chromatin Structure and Gene Expression
Mishkin, Mortimer 1/16/1991 NIH Memory Circuits
Piatigorsky, Joram 4/3/1991 NIH Gene Sharing: Lens Crystallins, Enzymes, and Stress Proteins
Anderson, W. French 3/25/1992 NIH Human Gene Therapy
Blaese, R. Michael 3/25/1992 NIH Human Gene Therapy
Rosenberg, Steven A. 3/25/1992 NIH Human Gene Therapy
Rapoport, Judith L. 1/26/1993 NIH Child Psychiatry and the Brain
Roberts, Anita B. 3/30/1994 NIH Transforming Growth Factor Beta: Past, Present, and Future
Sporn, Michael B. 3/30/1994 NIH Transforming Growth Factor Beta: Past, Present, and Future
Wurtz, Robert H. 1/18/1995 NIH Brain Maps for Eye Movements
Kunkel, Thomas A. 11/1/1995 NIH DNA Replication Fidelity, Mismatch Repair, and Genome Stability
Gallin, John I. 11/20/1996 NIH What Chronic Granulomatous Disease Has Taught Us about Oxidative Metabolism, Gamma-Interferon and Gene Therapy
Ungerleider, Leslie G. 2/25/1998 NIH Neural Mechanisms of Human Cognition: Insights from Brain Imaging Studies
Nussbaum, Robert L. 1/20/1999 NIH The Genetic Approach to Understanding Parkinson’s Disease
Balaban, Robert S. 2/2/2000 NIH Domestication of the Mitochondrion for Cellular Energy Conversion
Varmus, Harold 4/25/2001 NIH
Lowy, Doublas 2/13/2002 NIH Papillomavirus virus-like particles: for vaccines against HPV and other diseases
    NIH
The NIH Director's Lectures
Ochoa, Severo 1/21/1953
Tricarboxylic Acid Cycle: Enzymatic Mechanisms
Cori, Carl F. 9/24/1953
Enzymatic Analysis of the Structure of Starch and Glycogen
Gregg, Alan 9/30/1954
The Natural History of Changing One’s Job
Sabin, Albert B. 12/16/1954
Avirulent Strains of Poliomyelitis Virus--Segregation, Characterization, Role in Nature, and Potential Usefulness for Human Immunization
Dale, Sir Henry Hallett 5/31/1955
Some Recent Developments Concerning the Chemical Transmission of Nervous Effects
Pauling, Linus 5/1/1957
The Nature of Molecular Disease
Baker, W.O. 1/22/1958
Relation of Physical Science to Life Science: Communication Theory
Szent-Gyorgyi, Albert 5/14/1958
Bioenergetics
Hill, Archibald Vivian 10/7/1958
The Energy Exchanges Involved in Muscular Contraction and Nerve Conduction
Wald, George 5/5/1959
The Biochemical Evoltion of Vision
Kornberg, Arthur 10/13/1959
Biosynthesis of Deoxcyribonucleic Acid (DNA)
Eagle, Harry 2/9/1960
Biosynthesis in Human Cell Cultures
Smith, Homer W. 4/26/1960
From Fish to Philosopher
Kety, Seymour S. 5/18/1960 NIH The Biologist Examines the Mind and Behavior
Penfield, Wilder 10/4/1960
Conscious Experience--What the Brain Records and Where
Heppel, Leon A. 12/14/1960
An Enzymatic Approach to Nucleic Acid Chemistry
Edsall, John T. 1/25/1961
Inquiries Concerning the Fine Strucure of Protein Molecules
Huebner, Robert J. 3/15/1961
Viruses, Common Colds, and Cancer
Hertz, Roy 11/15/1961
Endocrine Aspects of the Cancer Problem
Ribi, Edgar E. 2/28/1962
Relationship Between Structure and Host Reactive Properties of Microorganisms
Calvin, Melvin 4/25/1962
Photosynthesis
Smadel, Joseph E. 12/12/1962
Intercellular Infection and the Carrier State
Stetten, DeWitt Jr. 2/27/1963 NIH The History and Natural History of Gout
Blalock, Alfred 9/5/1963
Cardiovascular Surgery--Past and Present
Nirenberg, Marshall, W. 12/4/1963 NIH On the Nature of the RNA Code
Monod, Jacques 2/19/1964
Controling Elements and Regulatory Circuits in Cellular Metabolism
Anfinsen, Christian B. 10/20/1964 NIH Some Biological Implications of Protein Structure
Hodgkin, Alan Lloyd 1/13/1965
Giant Nerve Fibres
Gross, Jerome 10/20/1965
Tissue Remodeling Mechanisms in Amphibian Metamorphosis
Billingham, Rupert E. 12/8/1965
Tissue Transplantation: Past, Present, and Future
Stadtman, Earl R. 11/2/1966 NIH The Celular Regulation of Branched Biosynthetic Pathways
Haskins, Caryl Parker 12/7/1966
The Natural History of Some Small Brains
Palade, George E. 2/8/1967
Recent Studies on Microsomes
Axelrod, Julius 10/25/1967 NIH The Pineal Gland, a Biological Clock
Ebert, James D. 12/13/1967
Developmental Biology: The Richness of New Opportunity
Skinner, Burrhus F. 2/21/1968
Operant Conditioning and the Management of Human Behavior
Meister, Alton 10/30/1968
On the Synthesis and Functions of Glutamine and Asparigine
Kac, Mark 2/12/1969
The Role of Mathematical Models in Science
Benzer, Seymour 4/22/1970
Genetic Dissection of Visual Behavior in Drosophila
Kuffler, Stephen William 10/21/1970
Viewing Living Synapses and Exploration of the Chemosensitivity of the Neuronal Surface
Horecker, Bernard L. 12/2/1970
Fructose Diphosphatase and the Control of Gluconeogenesis
Harris, Henry 10/7/1971
The Analysis of Malignancy by Cell Fusion
Sinsheimer, Robert L. 1/19/1972
The Replication of Single-Stranded DNA Bacteriophages:Facts and Riddles
Scholander, Per F. 10/25/1972
Tensile Water
Goodall, Jane 11/8/1972
Behavior of Chimpanzees and their Natural Habitat
Guillemin, Roger 4/11/1973
The Hormones of the Hypothalamus
Sela, Michael 12/12/1973
Probing Into Immunological Phenomena: From Molecule to Cell
Julian, Percy 3/20/1974
Some Phases of Oxidative Hydroxylationof Steroids in the Animal Organism
Bergstrom, Sune 4/24/1974
The Prostaglandins-Bioregulators With Clinical Implications
Racker, Efraim 3/26/1975
Ion Transport in Reconstituted Systems and in Cancer Cells
Wiesel, Torsten N. 4/9/1975
Visual Deprivation and Its Effects on the Monkey Striate Cortex
Berg, Paul 11/17/1976
Dissections and Reconstruction of the SV40 Genome
Edelman, Gerald M. 12/8/1976
Cell Surface Modulation
Kandel, Eric R. 3/29/1978
Cellular Insights into Behavior and Learning
Khorana, Har Gobind 5/10/1978
Total Synthesis of a Biologically Functional Gene
Mintz, Beatrice 12/6/1978
Turning Cancer Cells Into Mice
Schimke, Robert T. 5/2/1979
Gene Amplification and MethotrexateResistance in Cultured Mammalian Cells
Snyder, Solomon H. 9/12/1979
Drugs, Neurotrasmitters, and the Brain
Gilbert, Walter 11/28/1979
The Structure and Evolution of Genes
Blumberg, Baruch S. 5/7/1980
Hepatitis B Virus and the Pathogenesis and Prevention of Cancer in the Liver
Nathans, Daniel 10/1/1980
Mutational Analysis of a Viral Replicon
Ashwell, Gilbert 5/27/1981
The Current Status of the Hepatic Membrane Receptor for Desialylated Serum Glycoproteins
Goldstein, Joseph L. 12/2/1981
Cell Surface Receptors for Plasma Lipoproteins: Implications for Biology and Medicine
Koshland, Daniel E. Jr. 10/27/1982
Information Processing in a Simple Sensory System: Bacterial Chemotaxis
Steitz, Joan A. 11/17/1982
Autoantibodies as Probes for Small Ribonucleoproteins From Eukaryotes
Richards, Frederic M. 1/25/1984
Charge Distribution, Electrostatic Fields, and Enzyme Function
Bishop, J. Michael 3/21/1984
Cancer Genes Come of Age
Nottebohm, Fernando 11/7/1984
Neuronal Replacement in Adulthood and its Possible Relation to Learning
Axel, Richard 11/28/1984
Gene Expression in Developing and Adult Neurons
Kan, Yuet Wai 5/4/1986
Insights into the Genetics of Thalassemia
Leder, Philip 5/19/1986
Misplacing Genes
Moss, Bernard 1/14/1987 NIH Vaccinia Virus: From Jenner to Genetic Engineering
Notkins, Abner Louis 5/6/1987 NIH Tracking the Causes of Diabetes Mellitus: From Viruses to Autoimmunity
Berridge, Michael J. 9/23/1987
Inositol Lipids and Intracellular Communication
Cech, Thomas R. 11/2/1988 Univ. Colorado RNA as an Enzyme
Cohen, Stanley N. 9/20/1989 Stanford Analysis of Mammalian Gene Regulation in situ using Retrovirus-Based Portable Exons
Brown, Michael S. 1/17/1990 UTexas Genes that Control Cholesterol
Nathans, Jeremy 10/11/1990 Johns Hopkins Molecular Genetic Studies of Visual Pigments
Kunkel, Louis M. 11/14/1990 Harvard Dystrophin Abnormalities in Neuromuscular Disease
Koshland, Daniel E. Jr. 2/13/1991 AAAS Mechanisms of Short-term and Long-term Memory
Lefkowitz, Robert J. 5/13/1991 Duke The Adrenergic Receptors
Lee, Wen-Hwa 5/23/1991 UCSD Molecular Genetics of Cancer Suppression
Weissman, Irving L. 11/19/1991 Stanford Hematopoietic Stem Cells: Biological and Clinical Potentials
Gottesman, Michael M. 1/22/1992 NIH Molecular Analysis of Resistance to Anti-Cancer Drugs
Sharp, Phillip A. 5/6/1992 MIT Splicing of Nuclear Precursors to Messenger RNAs
Capecchi, Mario R. 5/21/1992 Univ. of Utah Creating Mice With Targetted Disruptions in Protooncogenes and Homeobox Genes
Bax, Adriaan 2/24/1993 NIH Protein NMR: Pushing Frontiers in Structural Biology
Clore, G. Marius 2/24/1993 NIH Protein NMR: Pushing Frontiers in Structural Biology
Gronenborn, Angela M. 2/24/1993 NIH Protein NMR: Pushing Frontiers in Structural Biology
Klausner, Richard D. 4/29/1993 NIH Iron, RNA, and Gene Expression: Solving the Dilemmas of a Toxic Nutrient
Nossal, Sir Gustav 5/12/1993 W&E.HallInst.MedRes Self Recognition:Recent Insights into the Deepest Puzzle in Immunology
Fauci, Anthony S. 5/19/1993 NIH Immunopathogenic Mechanisms of HIV Infection
Wong-Staal, Flossie 12/16/1993 UCSD Gene Therapy for AIDS: Fantasy or Feasibility?
Zoon, Kathryn C. 3/24/1994 CBER, FDA Human Interferon Alphas: The Legend and the Legacy
Donahoe, Patricia K. 4/21/1994 Harvard Regulation and Downstream Pathways of Growth Inhibitors
King, Mary-Claire 5/1/1994 Berkeley Genetics of Human Breast Cancer
Schatz, Carla J. 5/17/1995 Berkeley Brain Waves and Brain Wiring
Blackburn, Elizabeth H. 5/24/1995 UCSF Altering Telomerase RNA: Enzymatic and Cellular Consequences
Gehring, Walter J. 2/21/1996 Biozentrum The Master Control Gene for Morphogenesis and Evolution of the Eyes.
Neer, Eva J. 4/3/1996 Harvard Heterotrimeric G Proteins: Transmitters and Tuners for Membrane Signals.
Jessell, Thomas M. 3/19/1997 Columbia Inductive Signals and the Control of Neural Cell Fate
Blobel, Günter 3/26/1997 Rockefeller Protein Traffic Into and Out of the Nucleus
Folkman, M. Judah 11/19/1997 Harvard New Directions in Angiogenesis Research
Pawson, Anthony J. 2/4/1998 S.Lunenfield Res. Inst. Protein Modules in Signal Transduction
Lodish, Harvey F. 9/16/1998 MIT The Erythropoietin Receptor and the Control of Red Cell Production
Sherr, Charles J. 9/23/1998 St.JudeChild.Res.Hosp. Integration of Oncogenic Signals by the ARF and p53 Tumor Suppressors
Brundtland, Gro Harlem 10/29/1998 World Hlth Org. The New WHO and Partnerships for the Future
Buck, Linda D.B. 2/17/1999 Harvard Deconstructing Smell
Brown, Patrick O. 12/8/1999 Stanford The Living Genome
Bargmann, Cornelia 5/17/2000 UCSF Mechanisms of Odor Discrimination in C. Elegans
Kapikian, Albert 5/28/2000 NIH Etiology, Epidemiology, and Prevention of Viral Gastroenteritis
Cech, Thomas R. 9/20/2000 HHMI Life at the end of the chromosome: telomeres and telomerase
Zewail, Ahmed 5/2/2001 CalTech
Wilson, William Julius 5/16/2001 Harvard
Straus, Stephen 3/11/2002 NIH Exploring the Scientific Basis of Complementary and Alternative Medicine
Carlsson, Arvid 4/3/2002 Univ. of Goteborg A Paradigm Shift in Brain Research
Bronner-Fraser, Marianne 45/1/2002 Calif. Inst. of Technology Formation and Evolution of the Neural Crest
       
       

 

 

   
The Percy Julian Centennial Lecture
Prendergast, Franklyn 11/10/1999 Mayo Clinic Elegant Photophysics in the Green Fluorescent Protein
The NIH Director's Margaret Pittman Lectures
Dunbar, Bonnie S 11/26/1994 Baylor New frontiers in reproductive biology and contraceptive vaccines
Hogan, Brigid L.M. 2/28/1996 Vanderbilt BMPs: Multifunctional Regulators of Embryonic Development
Farquhar, Marilyn G. 5/4/1997 UCSD Control of Intracellular Membrane Traffic:Involvement of G Proteins, GAIP, and RGS Protein
Limbird, Lee E. 9/17/1997 Vanderbilt Alpha-2 Adrenergic Receptors Achieve Signaling Specificty via Coupling to Distinct Effectors and Targeting to Discrete Surface Domains
Prives, Carol L. 11/18/1998 Columbia Signaling to the p53 Tumor Suppressor Protein
Rowley, Janet 4/26/2000 Univ. of Chicago Cancer Cytogenetics: Is it Passé?
Hopkins, Nancy, H.D. 11/1/2000 MIT Insertional mutagenesis in Zebrafish nets genes for early vertebrate development
Kolb, Helga 5/29/2002 Univ. of Utah The organization of the Vertebrate Retina
       
       
The NIH Alumni Association Shannon Lectures
Rosenberg, Leon E. 10/26/1998 Princeton The Medical Research Enterprise--Only as Strong as its Clinical Links
Choppin, Purnell 11/17/1999 HHMI A role for Private Support of Biomedical Research
Angell, Macia 2/14/2001 Harvard The ethics of clinical trials
Colwell, Rita 11/27/2001 National Science Found. Crossing Borders: Science, the Public, and New Policies
       
       
The DeWitt Stetten, Jr. Lectures
Hogness, David S. 10/13/1982 Stanford A Molecular Analysis of Genes that Determine Developmental Pathways
Rich, Alexander 10/5/1983 MIT Left-Handed Z-DNA and the Regulation of Transcription
Stroud, Robert M. 10/31/1984 UCSF Celular Signaling: What Does the Structure of the Acetylcholine Receptor Tell Us About Its Function?
Brown, Donald D. 10/30/1985 Carnegie Inst. of Washington The Molecular Basis of Differential Gene Activity
Pardue: Mary Lou 10/8/1986 MIT Heat Shock: Cellular Response to Environmental Stress
McKnight, Steven L 11/7/1987 Univ. of Chicago What DNA Viruses are Telling Us about Genetic Regulation in Animal Cells
Ptashne, Mark S. 11/7/1987 Harvard How Proteins See DNA and Turn Genes On and Off
Sigler, Paul B. 11/7/1987 Carnegie Inst. of Washington The trp Repressor: The Chemical Details of a Genetic Switch
Dervan, Peter B. 10/12/1988 CalTech Sequence-Specific Recognition of DNA: A Synthetic Approach
Shapiro, Lucy 10/18/1989 Stanford The Control of Timing and Spatial Organization During Cellular Differentiation
Blackburn, Elizabeth H. 11/7/1990 UCSF Synthesis of Telomeres
Kirschner, Marc W. 10/23/1991 UCSF The Biochemical Machinery Regulating the Cell Division Cycle
Bailey, James E. 10/28/1992 SwissFed.Technical Univ. Cellular Biotechnology:Engineering Metabolism for Enhanced Productivity and New Products
Cech, Thomas R. 10/28/1992 Univ. Colorado RNA as an Enzyme: From Chemistry to Biotechnology
Shultz, Peter G. 10/28/1992 Berkeley Catalytic Antibodies
Guthrie, Christine 10/18/1993 UCSF The Spliceosome: A Dynamic Ribonucleoprotein Machine
Schreiber, Stuart L. 10/19/1994 Harvard A Chemical Approach to Understanding and Controlling Signal Transduction
Kim, Peter S. 10/18/1995 MIT Design of Proteins and Drugs
Olivera, Baldomero M. 11/23/1996 Univ. of Utah Using Deadly Cone Snails to Learn Drug Design and Probe Nervous Systems
Barton, Jacqueline K. 10/22/1997 CalTech DNA-Mediated Electron Transfer: Chemistry at a Distance
Lindquist, Susan 10/21/1998 Univ. of Chicago Mad Cows Meet Psi-Chotic Yeast: The Expansion of the Prion Hypothesis
Spudich, James 10/20/1999 Stanford Single-Molecule Biomechanics and the Myosin Family of Molecular Motors
Moore, Peter B. 10/18/2000 Yale The Complete Atomic Structure of the large ribosomal subunit from Haloarcula marismortui
Ramakrishnan, Venkatraman 10/18/2000 Cambridge Insights from the structure of the 30S Ribosomal subunit
Yonath, Ada E. 10/18/2000 Weizmann Inst. of Sci. Decoding the Genetic Information on ribosomes in Molecular Detail
Allis, C. David 10/17/2001 Univ. of Virgina Tranlating the Histone Code: A Tale of Tails
       
       
       
       
The Wednesday Afternoon Lectures
Tonegawa, Susumu 10/5/1994 MIT The role of peptides in the selection of thymocytes
Jurnak, Frances 10/12/1994 Univ.Calif. Riverside The parallel beta-helices of pectate lyases and implications for infectious agents
Glimcher, Laurie H. 11/2/1994 Harvard Costimulatory molecules B7-1 and B7-2 differently affect T-helper development and autoimmunity
Hartwell, Leland H. 11/9/1994 Univ. of Washington Cell cycle check points and cancer
Houseman, David E. 11/30/1994 MIT Role of apoptosis in cancer treatment
Baltimore, David 12/7/1994 MIT The role of NF-kappaB in the immune response
Steere, Allen C. Jr. 12/14/1994 Tufts Lyme Disease
DeRosier, David J. 12/21/1994 Brandeis The bacterial flagellum--nature's rotary motor
Herskowitz, Ira 1/11/1995 UCSF Control of cell cycle progression and cell polarity in yeast
Gilman, Alfred G. 1/25/1995 UTexas G proteins and regulation of adenylyl cyclases
Brugge, Joan S. 2/1/1995 Ariad Pharm. Inc. Regulation of tyrosine phosphorylation by integrin receptors
Björklund, Anders 2/8/1995 Univ. of Lund, Sweden Neural Grafting in Parkinson’s Disease
Delong, Mahlon R. 2/8/1995 Emory Surgical Approaches to Parkinson’s Disease
Choi, Dennis W. 2/15/1995 Washington Univ. Rendering the brain resistant to stroke
Scheller, Richard H. 2/22/1995 Stanford Membrane trafficking in the nerve terminal
Deisenhofer, Johann 3/1/1995 UTexas The 3-D structure of DNA photolyase: How light repairs DNA
Alberts, Bruce M. 3/8/1995 NAcad.Science The centrosome and the organization of the cytoplasm in the early Drosophila embryo
Bootsma, Dirk 3/15/1995 Erasmus DNA repair, transcription and chromatin structure: an intimate engagement
Horvitz, H. Robert 3/22/1995 MIT Genetic control of programmed cell death in C. elegans
Tjian, Robert 3/29/1995 Berkeley Mechanisms of transcriptional regulation: Assembly of activator, co-activator, and TAF complexes
Hynes, Richard O. 4/5/1995 MIT Murine mutations affecting cell adhesion
Kornfeld, Stuart 4/12/1995 Washington Univ. Signals that mediate the cellular trafficking of the mannose 6-phosphate receptor
Harlow, Edward E. 4/19/1995 Harvard The Retinoblastoma Protein
Meyer, Roger E. 5/3/1995 A.C. Nropsy.pharm. Alcohol treatment research: New prospects, new methods
Thomas, E. Donnel 5/10/1995 Univ. of Washington The history of the development of bone marrow transplantation and its application to the clinic
Squire, Larry R. 6/7/1995 UCSD Memory and Brain Systems
Steitz, Joan A. 6/14/1995 Yale snRNPs: Building Blocks of the Cell Nucleus
Roses, Allen D. 6/28/1995 Duke Apolipoprotein E and Alzheimer's disease: Clinical research points to new basic neuronal pathways
Riggs, B. Lawrence 9/20/1995 Mayo Clinic Mechanisms of estrogen action on bone at the tissue, cellular, and molecular levels
Darnell, James E. 10/11/1995 Rockefeller Signalling genes from the cell surface
Perlmutter, Roger M. 10/11/1995 Univ. of Washington Control of lymphocyte development by protein phosphorylation
Bustamante, Carlos J. 10/25/1995 Univ. of Oregon Imaging protein-nucleic acid complxes with the scanning force microscope
Walsh, Christopher T. 11/8/1995 Dana Farber Molecular mechanisms for bacterial resistance to the antibiotic vancomycin
Anderson, Richard G. 11/29/1995 UTexas Compartmentalization of Signal Transduction in Caveolae
Flavell, Richard A. 1/17/1996 Yale Genetic manipulation of immunity and autoimmunity
Cepko, Constance L. 1/24/1996 Harvard Cell fate determination in the vertebrate retina
Fink, Gerald R. 1/31/1996 MIT Signal transduction on the information superhighway controls yeast morphogenesis
Hernandez, Nouria 2/7/1996 Cold Spring Harbor Transcription initiation and elongation in the human snRNA genes and the HIV-1 LTR
Nemeroff, Charles B. 2/14/1996 Emory The hypothalamic-pituitary-adrenal axis and the pathophysiology of depression: The potential role of early adverse experience
McNaughton, Bruce L. 3/6/1996 Univ. of Arizona The hippocampus, space and memory: The stuff dreams are made of
Mekalanos, John J. 3/13/1996 Harvard Genetic approaches to understanding bacterial pathogenesis: Trying to teach the old dog (E. coli) some new tricks
Fuchs, Elaine V. 3/20/1996 Univ. of Chicago Of Mice and Men: Cytoskeleton and Disease
Goldberger, Ary L. 3/27/1996 Harvard Fractals in Medicine, Music and Art
Goldberger, Zack Davids 3/27/1996 Brown Fractals in Medicine, Music and Art
Barry, Daniel T. 4/3/1996 NASA Space Flight: A Physician-Scientist’s Perspective
Johnson, Louise N. 4/17/1996 Oxford Structural aspects of control by protein phosphorylation
Tallal, Paula 4/24/1996 Rutgers Neurobiological Basis of Speech
Raff, Martin C. 4/29/1996 UnivCol. London The Ins and Outs of Programmed Cell Death
Simon, Melvin I. 5/1/1996 CalTech Genetic approaches to the analysis of G-protein mediated signal transduction
Todd, John A. 5/5/1996 Oxford A genetic basis for familial clustering of type 1 diabetes
Kleckner, Nancy E. 5/8/1996 Harvard Interactions between and along chromosomes during meiosis
Rothman, James E. 5/15/1996 Memorial Sloan-Kettering
Melchers, Georg (Fritz) 5/22/1996 Basel Inst. The roles of surrogate light chain in B cell development
Rosenbusch, Jürg P. 5/26/1996 Biozentrum Molecular pathology of channel-forming transmembrane proteins at atomic resolution
Taniguchi, Tadatsugu 5/29/1996 Univ. of Tokyo The Molecular Basis of Cytokine Response
Frauenfelder, Hans 6/10/1996 Los Alamos NL Do We Finally Know How Myoglobin Works?
Mintz, Beatrice 6/12/1996 Fox Chase Melanoma development, metastasis, and treatment prospects in transgenic mouse models
Fulker, David W. 6/18/1996 Univ. Colorado Mapping the genetic contributions to complex behavioral traits
Cory, Suzanne 9/11/1996 W&E.HallInst.MedRes Regulation of Apoptosis by the Bcl-2 Family
Sanes, Joshua R. 9/11/1996 Washington Univ. Mutational Analysis of Synaptic Development
Chamberlin, Michael J. 10/2/1996 Berkeley The role of RNA Binding Sites in Elongation and Terminatin by RNA Polymerase
Berrettini, Wade H. 10/9/1996 Thomas Jefferson Genetic Analysis of Animal Models for Behavioral Disorders
Desrosiers, Ronald C. 10/16/1996 Harvard A Role for Auxiliary Genes in the Pathogenesis of AIDS
Stuart, Kenneth D. 10/30/1996 Univ. of Washington The Mechanism of mRNA Editing: gRNA-Specified Uridylate Insertion and Deletion
Mosmann, Tim R. 11/13/1996 Univ. of Alberta Immune Regulation by T Cell Subsets and their Cytokines
Hendrickson, Wayne A. 12/4/1996 Columbia Structural Biology of Signal Transduction Across Membranes
Smith, Janet L. 12/18/1996 Purdue Univ. Modular Organization in the Structure and Function of an Enzyme Family: The Glutamine Amidotransferases
Goodman, Corey S. 4/7/1997 Berkeley Wiring Up the Brain: Genetic Analysis of the Mechanisms Controlling the Generation of Neural Specificity
Pouyssegur, Jacques 4/7/1997 Univ. de Nice Growth Factor Signalling via MAP Kinases: Specificity and Spatiotemporal Action
Kimble, Judith 4/9/1997 Univ. of Wisconsin Regulation of Cell Fate in the Germ Line of the Nematode Caenorhabditis elegans
Milligan, Ronald A. 4/16/1997 Scripps How Myosin and Kinesin Motors Move
Brodsky, Frances M. 4/23/1997 UCSF Endocytosis: Mechanism and Subversion
Maniatis, Tom 4/30/1997 Harvard Combinatorial Mechanisms for Specific Gene Activation in Response to Extracellular Signals
Livingston, David M. 5/14/1997 Dana Farber Functional Analysis of the BRCA1 Gene Product
Goodfellow, Peter N. 5/18/1997 SmithKlineBeecham From Sex to Drugs
Bissell, Mina J. 5/21/1997 L.Berkeley NL The Central Role of ECM and Integrins in the Regulation of Tissue-Specific Genes, Apoptosis, and Cancer in the Mammary Gland
Walter, Peter 10/1/1997 UCSF Intracellular Signalling from the Endoplasmic Reticulum to the Nucleus
Wiley, Don C. 10/15/1997 Harvard Structure/Function Studies in MHC/Antigen Recognition and in Viral Entry Mechanisms
Beckwith, Jonathan R. 10/29/1997 Harvard Making, Breaking, and Shuffling Protein Disulfide Bonds in Vivo
Dervan, Peter B. 11/3/1997 CalTech Molecular Design for DNA Recognition: An Approach Toward Gene-Specific Transcription
Hildreth, James E.K. 11/5/1997 Johns Hopkins The Role of Host Adhesion Molecules in the Biology of Retroviruses
Wilson, James 11/12/1997 Univ. of Pennsylvania Cystic Fibrosis: Pathogenesis and Treatment
Simons, Kai 11/26/1997 EuroMolecBiol.Lab sphingolipid-cholesterol Rafts in Membrand Trafficking and Signalling
Singer, Wolf 12/3/1997 Max Planck The Putative Role of Response Syncronization in Cortical Processing
Rosenfeld, Michael Geoffrey 12/17/1997 UCSD Mechanisms of Transcriptional Control of Neural and Endocrine Development
Abelson, John 1/7/1998 CalTech The High Resolution Crystal Structure of an Archeal tRNA Splicing Endonuclease Provides New Insights in the Mechanism of tRNA Splicing in Eukaryotes
Lifton, Richard P. 1/14/1998 Yale The Molecular Genetics of Human Hypertension and Its Consequences
Mathis, Diane 1/21/1998 Univ. de Louis Pasteur A Stripped-down Model of Autoimmune Diabetes
Eberwine, James 1/26/1998 Univ. of Pennsylvania Molecular Biology of the Single Neuron: Insights into Neuronal Development and Neurological Disease
Anderson, Paul 1/28/1998 Amer. Chem. Soc. Discovery of HIV Protease Inhibitors
Moncada, Salvador 2/11/1998 Wellcome Res.Labs The Discovery of Nitric Oxide as a Biological Mediator: A 10-year Perspective
Bloom, Floyd E. 2/18/1998 AAAS Animal Models of Neuro-AIDS
White, Eileen P. 3/4/1998 Rutgers Regulation of Apoptosis by Oncogenes and Tumor Supressor Genes
Vale, Ronald D. 3/11/1998 UCSF The Molecular Mechanism of Kinesin-Driven Motility
Holden, Hazel M. 3/18/1998 Univ. of Wisconsin Carbamoyl Phosphate Synthetase: A 96å Journey from Substrate to Product
Jänisch, Rudolf 3/25/1998 MIT Mammalian X-Chromosome Inativation
Marrack, Philippa C. 4/1/1998 Univ. Colorado T Cells and How to Keep a Good Thing Going
Tonegawa, Susumu 4/8/1998 MIT Memory Mechanisms
Lander, Eric S. 4/15/1998 MIT Genes and Genomes
Niswander, Lee Ann 4/22/1998 Memorial Sloan-Kettering Molecular Control of Vertebrate Limb Development
Evans, Ronald M. 4/29/1998 Salk Institute Nuclear Receptors: A Superfamily
Zipursky, Larry 5/6/1998 UCLA Axon Guidance in the Drosophila Visual System
Basbaum, Allen I. 5/13/1998 UCSF The Neurochemistry of Altered Pain States
Crabtree, Gerald R. 5/17/1998 Stanford The Ca++/Calcineurin/NF/ATc Pathway in Development and Cell Proliferation
Goldman-Rakic, Patricia S. 5/20/1998 Yale Cellular Basis of Mental Phenomena
Ingber, Donald 5/27/1998 Harvard Integrins, Mechanical Forces, and Control of Gene Expression
Nathan, Carl 6/3/1998 Cornell Nitric Oxide and NO Resistance Genes: Lessons from Tuberculosis
Mombaerts, Peter 10/28/1998 Rockefeller Targeting Olfaction
Watson, James 11/9/1998 Cold Spring Harbor From the Double Helix to the Human Genome Project
Beachy, Phil 11/12/1998 Johns Hopkins Hedgehog Protein Biogenesis and Signaling
Eisenberg, David 11/25/1998 UCLA 3D Domain Swapping in Forming Normal and Pathological Protein Aggregates, and Interpreting Genome Sequences in Terms of 3D Structures
Schon, Eric 12/2/1998 Columbia Molecular Genetics of Human Mitochondrial Disease
Verma, Inder 12/9/1998 Salk Institute Gene Therapy: Problems and Prospects
Tsien, Roger Y. 1/13/1999 UCSD Imaging and Manipulating Protein Interactions and Gene Expression in Individual Cells
Goldman, Robert D. 1/14/1999 Northwestern Intermediate Filaments: From Cell Shape to DNA Replication
Smith, James 2/3/1999 RAND Pop.Res.Cen. Health and Economic Outcomes of New Immigrants
Ptashne, Mark S. 2/10/1999 Memorial Sloan-Kettering Imposing Specificity by Localization: Mechanism and Evolvability
Frackowiak, Richard 2/24/1999 UnivCol. London Visual Perception and Attention:Human Studies with Functional Neuroimaging
Alt, Frederick W. 3/3/1999 Harvard A Critical Role for DNA End-Joining Proteins in Both Lymphogenesis and Neurogenesis
Cantley, Lewis 3/10/1999 Harvard Role of PI3K in Cellular Regulation
Falkow, Stanley 3/17/1999 Stanford Probing the Intracellular Life of Bacteria
Aebi, Ueli 3/24/1999 MuellerInst. for MicStr. Structural and Functional Dissection of Nucleocytoplasmic Transport
Richmond, Tim 3/31/1999 Inst. Mol.Biol.Biophys.Zur Chromatin Crystallography:The 2.å X-ray Structure of the Nucleosome Core
Guarante, Leonard 4/7/1999 MIT Keeping Cells Alive: Is Caspase Inhibition Enough?
Martin, Gail R. 4/21/1999 UCSF FGF Gene Function in Vertebrate Gastrulation, Brain, and Limb Development
DeRobertis, Edward M. 5/2/1999 UCLA Patterning of the Vertebrate Embryo by Secreted Growth Factor Inhibitors
Takahashi, Joseph 5/7/1999 Northwestern Molecular Genetics of Circadian Clocks in Mammals
Emr, Scott D. 5/8/1999 UC LaJolla Links Between Cell Signaling, Membrane Trafficking and Tumor Progression
Matrisian, Lynn 5/12/1999 Vanderbilt Complex Roles for the Matrix Metalloproteinase Matrilysin in Tumor Progression
Gustafsson, Jan-Ake 5/19/1999 Karolinska New Dimensions in Nuclear Receptor Signalling
Imperiali, Barbara 5/23/1999 CalTech Chemistry and Biology of Asparginine-Linked Glycosylation
Mackinnon, Roderick 5/26/1999 Rockefeller Molecular Basis of K+ Conduction and Selectivity in Potassium Channels
Nasmyth, Kim 5/30/1999 Res.Inst.of Molec.Path.Vienna Separating Sister Chromatids
Schultz, Wolfram 9/15/1999 Univ. Fribourg Reward Processing in Primate Basal Ganglia and Frontal Cortex
Zakian, Virginia 10/13/1999 Princeton A Tale of Two Helicases: The saccharomyces Pif1p and Rrm3p Helicases Have Antagonistic Effects on Replication of Both Telomeric and Ribosomal DNA
Mitchison, Tim 10/28/1999 Harvard Biochemical and Small Molecule Approaches to Dissecting Mitosis
Hartwell, Leland H. 11/2/1999 Univ. of Washington Studying the Fundamentals of Cancer in Yeast
Tilghman, Shirley 12/1/1999 Princeton The Mechanism and Function of Genomic Imprinting in Mammals
Harrison, Stephen 12/15/1999 Harvard Viruses as Molecular Machines
Friedman, Jeffrey 1/12/2000 Rockefeller Leptin and the Neural Circuit Regulating Body Weight
Lanzavecchia, Antonio 1/19/2000 Inst.Res.Biomed.Bellinzona From Synapses to Immunological Memory
Tessier-Lavigne, Marc 2/9/2000 UCSF Wiring the Brain: Molecular Mechanisms of Axon Guidance in Vertebrates
Schlessinger, Joseph 2/16/2000 NYU Cellular Signalling by Tyrosine Phosphorylation
Nelson, David L. 2/23/2000 Baylor The Human as a Model System in Genetics: Examples from Fragile X Syndrome and incontinentia pigmenti
Blobel, Günter 3/1/2000 Rockefeller Traffic into and out of the Nucleus
Gearhart, John 3/8/2000 Johns Hopkins Human Pluripotential Stem Cells
Gibson, Gary 3/15/2000 Cornell Oxidative Processes and Signal Transuction in Alzheimer’s Disease: Insights from Brains, Peripheral Cells, and Animal Models
Blau, Helen 3/22/2000 Stanford Research Advances and Clinical and Public Health Implications of Genetic Therapy
Baumeister, Wolfgang 3/29/2000 Max Planck The Proteasome: Structural Basis of its Functional Repertoire
Shapiro, Lucy 4/5/2000 Stanford Protein Localization and Cell Differentiation During the Cell Cycle
Damsky, Caroline 4/19/2000 UCSF A Fibronectin-FAK Signaling Axis: How Special Is It?
Scheller, Richard H. 5/10/2000 Stanford Molecular Mechanisms of Membrane Trafficking and Exocytosis
Cantrell, Doreen 5/24/2000 Imp.CancerRes.Fund Spatial and Temporal Aspects of Antigen Receptor Signal Transduction
Nurse, Paul 5/31/2000 Imp.CancerRes.Fund Controlling the Fission Yeast Cell Cycle
Dixit, Vishva 6/14/2000 Genentech Identification of Components of the Cell Death Pathway
Fersht, Alan 6/21/2000 Cambridge Stability and Activity of the Tumor Supressor p53
Carlson, John 9/27/2000 Yale Olfaction in Drosophila: Genetics and eGenetics
Haase, Ashley T. 10/25/2000 Univ. of Minnesota Visualizing lentivirus infections: Lux et veritas in vivo
Craig, Nancy L. 11/8/2000 Johns Hopkins Tn7: A smarter transposon
Selkoe, Dennis 11/15/2000 Harvard Presenilins, Notch and the genesis and treatment of Alzheimer’s Disease
Bonhoeffer, Tobias 11/29/2000 Max Planck A thorny path to memories: Dendritic spines, neurotrophins and their role in synaptic plasticity
Seidman, Christine E. 12/20/2000 Harvard Gene mutations that remodel the heart
Meaney, Michael J.P. 1/3/2001 McGill University Maternal care, gene expression and neural development
Hillier, Sharon S. 1/10/2001 Univ. of Pittsburgh Topical microbicides: An HIV prevetntion strategy for the new millenium
Doherty, Peter C. 1/17/2001 St.JudeChild.Res.Hosp. Characters and limitations of the CD8+ T Cell response in acute and persistent viral infections
Schuepbach, Trudi M. 1/24/2001 Princeton Signaling through the EGF receptor and the establishment of the Dorso-ventral pattern in Drosophila oogenesis
Borisy, Gary G. 1/31/2001 Univ. of Wisconsin Actin Machinery: Pushing the Envelope
Scrimshaw, Susan 2/7/2001 Univ. of Illinois Beyond health disparities: Behavior and cultural diversity in health
Kiessling, Laura L. 2/21/2001 Univ. of Wisconsin Tuning signal transduction with synthetic ligands
Doudna, Jennifer A. 2/28/2001 Yale Structural insights into signal recognition particle function
Tabin, Clifford 3/14/2001 Harvard Signals patterning the vertebrate embryo
Jacks, Tyler 3/21/2001 MIT Modeling cancer in the mouse
Nelson, W. James 3/28/2001 Stanford Cell-cell adhesion and the development of epithelial cell polarity
Rine, Jasper 4/4/2001 Berkeley
Nicoll, Roger 4/11/2001 UCSF Synaptic plasticity and the redistribution of glutamate receptors
Duster, Troy 5/9/2001 Berkeley Buried Alive! The concept of race in science
Padan, Etana 5/13/2001 Hebrew Univ. of Jerusalem
Blakemore, Karin 5/23/2001 Johns Hopkins
Davis, Mark M. 5/30/2001 Stanford
Unwin, Nigel 6/20/2001 Cambridge
Leder, Philip 6/27/2001 Harvard Cancer: An Unfortunate Genetic Collaboration
A. James Hudspet 4/24/2001 Rockefeller Univ. How the Ear's Works Work: Transduction and Amplification by Hair Cells
Miller, Chris   Brandeis Univ. Ion channel Proteins: Function to Structure and Back Again
Young, Richard 9/26/2001 MIT Regulation of Genome Expression in Living Eukaryotic Cells
Carson, Ben 10/24/2001 Johns Hopkins Aspects of Pediatric Epilepsy Surgery
Thornton, Janet 10/31/2001 Univ. College, London Protein Folds, Functions, and Evolution
Cozzarelli, Nick 12/5/2001 Berkeley Mechanisms of DNA Unlinking and Chromosome Segregation
Olson, Wilma K. 12/12/2001 Rutgers DNA Mechanics and Gene Regulation
Aguzzi, Adriano 1/8/2002 Universitats Spital Zurich Immunobiology of Prion Diseases
Shatz, Carla 1/16/2002 Harvard Brain Waves and Immune Genes in Brain Wiring During Development
Michel, Hartmut 1/18/2002 Max-Planck Inst fur Biophysik Crystallization, Structures and Mechanisms of the Membrane Protein Complexes from the Respiratory Chain
Jackson, James 1/23/2002 Univ. of Michigan Race and Ethnic Disparities in Physical and Mental Health: The National Survey of American Life
Piston, David 1/30/2002 Vanderbilt University Imaging the Dynameic of Living Systems from Single Cells to Whole Animals
Nestler, Eric 2/6/2002 UT Southwestern Med Cen Molecular Basis of Addictive States
Dunston, Georgia 2/20/2002 Howard University Biomedical Significance of DNA Polymorphisms
Chakravarti, Aravind 2/27/2002 Johns Hopkins Genetic Architecture of Complex Disease: Simple or Complex?
Graybiel, Ann 3/6/2002 MIT Neural Mechanisms of Habit Formation: Plasticity in Cortico-Basal Ganglia Loops
McKnight, Steve 3/13/2002 UT Southwestern Med Cen Ideas on How Circadian Rhythm is Reciprocally Linked to Metabolism
Cresswell, Peter 3/20/2002 Yale Redox Reactions in Antigen Processing
Littman, Dan 3/27/2002 NYU Medical Center Epigenetic Regulation in T Cell Development
Pfeffer, Suzanne 4/10/2002 Stanford Regulation of Receptor Trafficking by Rab GTPases
Pace, Norman R 4/17/2002 Univ. of Colorado Molecular Microbial Ecology: In Hot Springs and Human Disease
Mooney, David 5/8/2002 University of Michigan Cell Instructive Materials for Tissue Engineering and Regeneration
Weissman, Irving 5/15/2002 Stanford Biology and Transplantation of Stem and Progenitor Cells
Evan, Gerard 5/22/2002 UCSF Life and Death of a Cancer Cell
Farmer, Paul 5/24/2002 Harvard Infections and Inequalities: The Challenge for Biosocial Research
Rapoport, Tom 6/11/2002 Harvard Protein Transport In and Out of the ER
Lefkowitz, Robert 6/19/2002 Duke Univ. Med Center Arrestins: Traffic Cops of Cell Signallling